In vivo micro-CT imaging of liver lesions in small animal models

摘要: Three-dimensional micro computed tomography (microCT) offers the opportunity to capture images liver structures and lesions in mice with a high spatial resolution. Non-invasive microCT allows for accurate calculation of vessel tortuosity density, as well lesion volume distribution. Longitudinal monitoring is also possible. However, distinguishing from variations within normal impossible by without use liver- or tumor-specific contrast-enhancing agents. The combination morphologic imaging functional imaging, such positron emission (PET) single photon (SPECT), better abdominal assessment structure discrepancies visible imaging. This paper describes methods current options compared other techniques small animals.