Alternatives to Fluoride in the Prevention and Treatment of Dental Erosion

摘要: In recent years, different agents have been discussed as potential alternatives to fluoride in the prevention of dental erosion. These are intended form acid-resistant layers on surface, induce repair eroded lesions by mineral precipitation or prevent enzymatic degradation demineralised collagen. The application adhesives and/or fissure sealants is considered be an effective alternative fluoride, but requires professional and, depending product used, a re-sealing surface every several months. Studies testing film-forming products, such polymers, suggested effectiveness some these approaches, chitosan, although further studies needed confirm this approach. Other demonstrated that products designed deliver calcium phosphate not successful at providing significant anti-erosive effect. advanced erosive lesions, collagenous dentine matrix can degraded host enzymes metalloproteinases (MMPs). As well fluorides, epigallocatechin gallate and chlorhexidine identified MMP inhibitors, with reduce progression While compounds shown potential, particularly those containing tin, approaches provide even greater protective capacity still need developed proven effective.