A Slightly Low Hemoglobin Level Is Beneficially Associated with Arterial Stiffness in Japanese Community-Dwelling Women

作者: Ryuichi Kawamoto , Yasuharu Tabara , Katsuhiko Kohara , Tetsuro Miki , Tomo Kusunoki

DOI: 10.3109/10641963.2011.618202

关键词:

摘要: Pulse wave velocity (PWV) is a simple and noninvasive method of measuring arterial stiffness for the assessment cardiovascular disease in high-risk populations. This association may be further confounded by hemoglobin status, which involved development atherosclerosis. We randomly recruited 120 men 223 women aged 69 ± 9 68 7 years, respectively, during their annual health examination single community. Arterial was evaluated brachial-ankle PWV (baPWV). The value baPWV different from women. In men, not related to levels (r = 0.013, P .886), but increased significantly progressively with 0.276, < .001). Stepwise multiple regression analysis using as objective variables, adjusted confounding factors explanatory showed that only women, (β 0.165, .001) well age 0.268, .001), body mass index (BMI; β -0.165, systolic blood pressure (SBP; 0.429, prevalence antihypertensive 0.154, .002), heart rate (HR; 0.108, .017), antilipidemic medication 0.094, .036), estimated glomerular filtration (eGFR; -0.147, .003) were independently associated baPWV. Multivariate-adjusted higher groups ≥12.7 g/dL (Group-2, Group-4) than lowest group (10.0-12.6 g/dL; .032). A slightly low level beneficially community-dwelling men.

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