Epidermal growth factor receptor immunostaining and epidermal growth factor receptor-tyrosine kinase activity in proliferative and neoplastic human endometrium.

作者: Roman Miturski , Andrzej Semczuk , Krzysztof Postawski , Jerzy Andrzej Jakowicki

DOI: 10.1159/000030141

关键词:

摘要: Epidermal growth factor receptor (EGFR) expression and EGFR-tyrosine kinase (EGFR-TK) activity were measured in proliferative (n = 12) neoplastic 31) human endometrium. Immunoreactivity of EGFR was related to clinicopathological features, estrogen (ER) progesterone (PR) status, patient outcome. All 27 specimens expressed the EGFR. Expression higher endometrium than endometrial cancer (p

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