作者: Richard B Freeman Jr , Erick B Edwards
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摘要: Factors associated with the risk for mortality once placed on liver transplant waiting list and how this relates to center-specific time activity have not been adequately evaluated. We performed study determine association between among candidates stratified by medical urgency at of registration. A Cox proportional hazards model was used calculate 2-year a cohort 16,414 registrants added United Network Organ Sharing January 1, 1997, December 31, 1997. After controlling confounding variables, we calculated centers, organ procurement organizations (OPOs), states. The relation median or determined linear regression. In multivariate analyses, higher initial status (relative [RR] = 12.8;P < .001), increasing age (P black ethnicity (RR 1.29; P history previous 1.2; .009), certain diagnoses, smaller center size 1.39; .008) were significantly increased mortality. Candidates blood type 0.87; .001) those cholestatic cirrhosis as primary diagnosis 0.73; 0.001) had reduced dying. There significant variations in OPOs, However, when entry, transplantation rates accounted almost none Although there are states, is very little urgency. Waiting should influence allocation policy. (Liver Transpl 2000;6:543-552.)