Dietary co-exposure to methylmercury and monosodium glutamate disrupts cellular and behavioral responses in the lobster cockroach, Nauphoeta cinerea model.
作者： Blessing A Afolabi , Isaac A Adedara , Diogo O Souza , João BT Rocha , None
DOI: 10.1016/J.ETAP.2018.09.003
关键词:
摘要: Abstract The present study aims to investigate the effect of monosodium glutamate (MSG) both separately and combined with a low dose methylmercury (MeHg) on behavioral biochemical parameters in Nauphoeta cinerea (lobster cockroach). Cockroaches were fed basal diet alone, + 2% NaCl, MSG; diet + 0.125 mg/g MeHg, MeHg NaCl; MSG for 21 days. Behavioral such as distance traveled, immobility turn angle automatically measured using ANY-maze video tracking software (Stoelting, CO, USA). Biochemical end-points acetylcholinesterase (AChE), glutathione-S-transferase (GST), total thiol TBARS also evaluated. Results show that MeHg + NaCl, increased traveled while MeHg + MSG time immobile. AChE activity was significantly reduced cockroaches across all groups when compared control. There no significant alteration GST levels. It could be NaCl potentiates neurotoxic cockroaches.
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