Antimicrobial activities of an oxygenated cyclohexanone derivative isolated from Amphirosellinia nigrospora JS‐1675 against various plant pathogenic bacteria and fungi

摘要: AIMS To evaluate the antimicrobial activities of an active compound isolated from culture broth Amphirosellinia nigrospora JS-1675 against various plant pathogenic bacteria and fungi. METHODS AND RESULTS While screening for bioactive secondary metabolites endophytic fungi, we found that A. showed strong in vitro antibacterial activity Ralstonia solanacearum. One (1) was identified as (4S, 5S, 6S)-5,6-epoxy-4-hydroxy-3-methoxy-5-methyl-cyclohex-2-en-1-one. Growth most tested phytopathogenic inhibited by 1 ethyl acetate (EtOAc) layer except Pseudomonas syringae pv. lachrymans. Compound also mycelial growth several Both EtOAc reduced bacterial leaf spot disease in detached peach leaves. They suppressed development wilt on tomato seedlings quite effectively. CONCLUSIONS fungi producing 1. SIGNIFICANCE IMPACT OF THE STUDY This is first report occurrence its efficacy Their control suggests this fungus can be used a microbial bactericide.