Two new isopimarane diterpenoids from the endophytic fungus Xylaria sp. SNB-GTC2501
作者： Jonathan Sorres , Charlotte Nirma , Seindé Touré , Véronique Eparvier , Didier Stien
DOI: 10.1016/J.TETLET.2015.06.022
关键词: Endophytic fungus 、 Stereochemistry 、 Xylaria sp. 、 Ergosterol peroxide 、 Absolute configuration 、 Antimicrobial 、 Chemistry
摘要: Abstract Two new isopimarane diterpenoids, xylabisboein A ( 1 ) and B 2 ), as well three known secondary metabolites (i.e., (−)-5-methylmellein 3 mellein-5-carboxylic acid 4 ergosterol peroxide 5 )), were isolated from a solid culture of the endophytic fungus Xylaria sp. SNB-GTC2501. The structures elucidated by spectroscopic analysis absolute configuration was determined X-ray crystallographic analysis. All compounds tested for their antimicrobial cytotoxic activities.
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