Two New Isopimarane Diterpenoids from the Endophytic Fungus Xylaria sp. SNB-GTC2501.

作者: Jonathan Sorres , Charlotte Nirma , Seinde Toure , Veronique Eparvier , Didier Stien

DOI: 10.1002/CHIN.201545209

关键词: Xylaria sp.AntimicrobialAbsolute configurationEndophytic fungusErgosterol peroxideStereochemistryTerpeneChemistry

摘要: Abstract Two new isopimarane diterpenoids, xylabisboein A ( 1 ) and B 2 ), as well three known secondary metabolites (i.e., (−)-5-methylmellein 3 mellein-5-carboxylic acid 4 ergosterol peroxide 5 )), were isolated from a solid culture of the endophytic fungus Xylaria sp. SNB-GTC2501. The structures elucidated by spectroscopic analysis absolute configuration was determined X-ray crystallographic analysis. All compounds tested for their antimicrobial cytotoxic activities.

参考文章(1)
Jonathan Sorres, Charlotte Nirma, Seindé Touré, Véronique Eparvier, Didier Stien, Two new isopimarane diterpenoids from the endophytic fungus Xylaria sp. SNB-GTC2501 Tetrahedron Letters. ,vol. 56, pp. 4596- 4598 ,(2015) , 10.1016/J.TETLET.2015.06.022