Colloidal dispersions of perfluoropentane

摘要: Agents for enhancing the contrast in a diagnostic ultrasound procedure comprise colloidal dispersions of liquid-in-liquid type, i.e., emulsions or microemulsions, which dispersed liquid phase is having boiling point below temperature animal to be imaged and therefore undergoes change from highly echogenic gaseous foam kugelschaum following administration animal. The state allows one manufacture extremely stable, pharmaceutically acceptable with particle sizes typically 1000 nm. at body yields microbubbles, 10,000 nm diameter, are effective as agents. Intravenous, intraarterial, oral, intraperitoneal, intrauterine dosage forms, methods administration, imaging techniques described.