Proteins Involved in Motility and Sperm-Egg Interaction Evolve More Rapidly in Mouse Spermatozoa

摘要: Proteomic studies of spermatozoa have identified a large catalog integral sperm proteins. Rapid evolution these proteins may underlie adaptive changes traits involved in different events leading to fertilization, although the selective forces underlying such rapid are not well understood. A variety differentially affect several steps ending thus resulting compartmentalized adaptation Here we analyzed genes associated various sperm’s life, from formation sperm-egg interaction. Evolutionary analyses were performed on gene sequences 17 mouse strains whose genomes been sequenced. Four derived wild Mus musculus, M. domesticus, castaneus and spretus. We found higher proportion exhibiting signature positive selection among those related motility Furthermore, interaction exhibited accelerated comparison other events. Thus, set candidate for future comparative genotype-phenotype associations species subjected sexual pressures. Adaptive could be driven by competition, since this force is known increase motile their swimming velocity. On hand, gamete coevolving with egg partners through episodes or conflict species-specific interactions barriers preventing interspecies fertilization.