Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome.
作者： Martyn T. Cobourne , Guilherme M. Xavier , Michael Depew , Louise Hagan , Jane Sealby
DOI: 10.1016/J.YDBIO.2009.04.021
关键词:
摘要: … palate and arrested tooth development. Significantly, … apoptosis and subsequent palatal shelf fusion. In contrast, high levels of Shh in odontogenic epithelium arrests tooth development …
core.ac.uk
elsevier.com
researchgate.net 
sci-hub.se 参考文章(78)
José Manuel Aguirre Urizar, Amelia Acha Sagredo, Olatz García Arregui, Sergio Zepeda Nuño, Aitziber Ortega García de Amezaga, Gorlin-Goltz syndrome: clinicopathologic aspects. Medicina Oral Patologia Oral Y Cirugia Bucal. ,vol. 13, pp. 2- ,(2008)
Andrew P McMahon, Philip W Ingham, Clifford J Tabin, Developmental roles and clinical significance of hedgehog signaling. Current Topics in Developmental Biology. ,vol. 53, pp. 1- 114 ,(2003) , 10.1016/S0070-2153(03)53002-2
Robert J. Gorlin, Nevoid basal cell carcinoma syndrome. Dermatologic Clinics. ,vol. 13, pp. 113- 125 ,(1995) , 10.1016/S0733-8635(18)30114-1
Graeme Suthers, Carol Wicking, Ian Macleod Smyth, Georgia Chenevix-Trench, Kylie Negus, Susan Shanley, Brandon Wainwright, Susan Gillies, Matt Edwards, Neva Haites, Scott Graham, Most germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a premature termination of the patched protein, and no genotype-phenotype correlations are evident American Journal of Human Genetics. ,vol. 60, pp. 21- 26 ,(1997)
Pao-Tien Chuang, Andrew P. McMahon, Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein Nature. ,vol. 397, pp. 617- 621 ,(1999) , 10.1038/17611
Mark J. Bitgood, Andrew P. McMahon, HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo Developmental Biology. ,vol. 172, pp. 126- 138 ,(1995) , 10.1006/DBIO.1995.0010
Wojtek Auerbach, Wojtek Auerbach, C. Brian Bai, C. Brian Bai, Alexandra L. Joyner, Daniel Stephen, Daniel Stephen, Joon S. Lee, Joon S. Lee, Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway Development. ,vol. 129, pp. 4753- 4761 ,(2002) , 10.1242/DEV.129.20.4753
Rong Mo, Anne Marie Freer, Dawn L Zinyk, Michael A Crackower, Jacques Michaud, Henry H-Q Heng, Ki Wai Chik, Xiao-Mei Shi, L.-C. Tsui, Shuk Han Cheng, Alexandra L Joyner, C.-C. Hui, Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development. Development. ,vol. 124, pp. 113- 123 ,(1997) , 10.1242/DEV.124.1.113
Forugh Vaziri Sani, Kristina Hallberg, Brian D. Harfe, Andrew P. McMahon, Anders Linde, Amel Gritli-Linde, Fate-mapping of the epithelial seam during palatal fusion rules out epithelial-mesenchymal transformation. Developmental Biology. ,vol. 285, pp. 490- 495 ,(2005) , 10.1016/J.YDBIO.2005.07.027
Erich Roessler, Elena Belloni, Karin Gaudenz, Philippe Jay, Philippe Berta, Stephen W Scherer, Lap-Chee Tsui, Maximilian Muenke, None, Mutations in the human Sonic Hedgehog gene cause holoprosencephaly. Nature Genetics. ,vol. 14, pp. 357- 360 ,(1996) , 10.1038/NG1196-357