Applications of Nanodiamonds in the Detection and Therapy of Infectious Diseases.

作者: Eva Torres Sangiao , Alina Maria Holban , Mónica Cartelle Gestal

DOI: 10.3390/MA12101639

关键词:

摘要: We are constantly exposed to infectious diseases, and they cause millions of deaths per year. The World Health Organization (WHO) estimates that antibiotic resistance could 10 million year by 2050. Multidrug-resistant bacteria the infection in at least one three people suffering from septicemia. While antibiotics powerful agents against alarming increase is great concern. Alternatives desperately needed, nanotechnology provides a opportunity develop novel approaches for treatment diseases. One most important factors prognosis an caused resistant early rigorous diagnosis, jointly with use therapeutic systems can specifically target pathogen limit selection strains. Nanodiamonds be used as antimicrobial due some their properties including size, shape, biocompatibility, which make them highly suitable development efficient tailored nanotherapies, vaccines or drug delivery systems. In this review, we discuss beneficial findings made nanodiamonds field, focusing on diagnosis also highlight innovative platform confer vaccine improvement, delivery, shuttle systems, well role generation faster more sensitive clinical diagnosis.

参考文章(77)
Olga A. Shenderova, Gary E. McGuire, Science and engineering of nanodiamond particle surfaces for biological applications (Review). Biointerphases. ,vol. 10, pp. 030802- 030802 ,(2015) , 10.1116/1.4927679
Manakamana Khanal, Viktoria Raks, Rahaf Issa, Volodymyr Chernyshenko, Alexandre Barras, Jose M. Garcia Fernandez, Lyuba I. Mikhalovska, Volodymyr Turcheniuk, Vladimir Zaitsev, Rabah Boukherroub, Aloysius Siriwardena, Ian R. Cooper, Peter J. Cragg, Sabine Szunerits, Selective Antimicrobial and Antibiofilm Disrupting Properties of Functionalized Diamond Nanoparticles Against Escherichia coli and Staphylococcus aureus Particle & Particle Systems Characterization. ,vol. 32, pp. 822- 830 ,(2015) , 10.1002/PPSC.201500027
Julia Wehling, Ralf Dringen, Richard N. Zare, Michael Maas, Kurosch Rezwan, Bactericidal Activity of Partially Oxidized Nanodiamonds ACS Nano. ,vol. 8, pp. 6475- 6483 ,(2014) , 10.1021/NN502230M
Sue D. Xiang, Anja Scholzen, Gabriela Minigo, Cassandra David, Vasso Apostolopoulos, Patricia L. Mottram, Magdalena Plebanski, Pathogen recognition and development of particulate vaccines: does size matter? Methods. ,vol. 40, pp. 1- 9 ,(2006) , 10.1016/J.YMETH.2006.05.016
Xue-Qing Zhang, Mark Chen, Robert Lam, Xiaoyang Xu, Eiji Osawa, Dean Ho, Polymer-Functionalized Nanodiamond Platforms as Vehicles for Gene Delivery ACS Nano. ,vol. 3, pp. 2609- 2616 ,(2009) , 10.1021/NN900865G
Santiago Rojas, Juan D. Gispert, Roberto Martín, Sergio Abad, Cristina Menchón, Deborah Pareto, Víctor M. Víctor, Mercedes Álvaro, Hermenegildo García, J. Raúl Herance, Biodistribution of amino-functionalized diamond nanoparticles. In vivo studies based on 18F radionuclide emission. ACS Nano. ,vol. 5, pp. 5552- 5559 ,(2011) , 10.1021/NN200986Z
Jing Li, Ying Zhu, Wenxin Li, Xiaoyong Zhang, Yan Peng, Qing Huang, Nanodiamonds as intracellular transporters of chemotherapeutic drug Biomaterials. ,vol. 31, pp. 8410- 8418 ,(2010) , 10.1016/J.BIOMATERIALS.2010.07.058
Qingwei Zhang, Vadym N. Mochalin, Ioannis Neitzel, Isabel Y. Knoke, Jingjia Han, Christopher A. Klug, Jack G. Zhou, Peter I. Lelkes, Yury Gogotsi, Fluorescent PLLA-nanodiamond composites for bone tissue engineering. Biomaterials. ,vol. 32, pp. 87- 94 ,(2011) , 10.1016/J.BIOMATERIALS.2010.08.090
G. Reina, S. Orlanducci, C. Cairone, E. Tamburri, S. Lenti, I. Cianchetta, M. Rossi, M. L. Terranova, Rhodamine/Nanodiamond as a System Model for Drug Carrier. Journal of Nanoscience and Nanotechnology. ,vol. 15, pp. 1022- 1029 ,(2015) , 10.1166/JNN.2015.9736