The anticonvulsant activity of cannabidiol and cannabinol

作者: Ralph Karler , William Cely , Stuart A. Turkanis

DOI: 10.1016/0024-3205(73)90141-0

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摘要: Abstract The anticonvulsant activity of delta-9-tetrahydrocannabinol was compared with that two other naturally occurring cannabinoids, cannabidiol and cannabinol, in a maximal electroshock test mice. drugs were administered as an emulsion sesame seed oil, Tween 80 saline to mice i.p. results indicate all three cannabinoids are effective anticonvulsants. time for peak effect is about 2 hr. In terms relative potencies, delta-9-THC similar but both them more active than cannabinol.

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