Pharmacologically active compounds
作者： Richard A. G. Smith
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摘要: A derivative of streptokinase-human plasminogen activator complex, in which the active catalytic site essential for fibrinolytic activity is blocked by a 2- or 4-aminobenzoyl group, useful treating venous thrombosis. The blocking group removable hydrolysis such that first order rate range 0.7×10 -5 sec -1 to 2.5×10 isotonic aqueous media at pH 7.4 37° C.
lens.org 参考文章(3)
Richard Anthony Godwin Smith, Enzyme derivatives for use in the treatment of venous thrombosis, compositions containing them and their preparation ,(1979)
Richard Anthony Godwin Smith, John Gordon Winchester, Enzyme derivatives, and their preparation ,(1980)
Richard A. G. Smith, Enzyme derivatives for use in the treatment of venous thrombosis ,(1980)