Antioxidant and α-amylase inhibitory activities of extract and isolates from Zygogynum pancheri subsp. arrhantum

作者: Henda Keskes , Marc Litaudon , Atef Cherif , Sahla Belhadj , Besma Hamdi

DOI: 10.1080/10286020.2014.938646

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摘要: One new sesquiterpenoid (5R*,8R*,9R*,10R*)-cinnamolide (8), and seven known compounds, 5-hydroxy-7-methoxyflavonone (1), 8-hydroxy-3-(4′-hydroxyphenyl)-6,7-(2″,2″-dimethylchromene)-tetralone (2), 8-hydroxy-3-(3′,4′-dihydroxyphenyl)-6,7-(2″,2″-dimethylchromene)-tetralone (3), 1β-E-O-p-methoxycinnamoyl-bemadienolide (4), 1β-O-(E-cinnamoyl)-6α-hydroxy-9-epi-polygodial (5), 1β-O-(E-cinnamoyl)-6α-hydroxypolygodial (6), 1β-O-E-cinnamoylpolygodial (7) were isolated from the ethyl acetate extract of barks Zygogynum pancheri subsp. arrhantum (Winteraceae). The structures these molecules assigned predominantly based on spectral data. structure compound 8 was confirmed by X-ray crystallographic analysis. Compounds 2 3 exhibited significant antioxidant activity, whereas compounds 1 4–7 showed α-amylase inhibitory activity.

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