Baculoviruses as Vectors in Mammalian Cells

作者: Chang-yong Liang , Xin-wen Chen

DOI: 10.1007/S12250-007-0016-1

关键词:

摘要: The Baculoviridae are a large family of enveloped DNA viruses exclusively pathogenic to arthropods. Baculoviruses have been extensively used in insect cell-based recombinant protein expression system and as biological pesticides. They deomostrated be safe mammals, birds fish. Recently, baculoviruses has shown transduce different mammalian cells spite the fact that they cannot replicate (11, 73, 76). This resulted development systems even vestors for gene therapy.

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