Prognostic factors for survival in patients with high-grade osteosarcoma using the Surveillance, Epidemiology, and End Results (SEER) Program database

摘要: Abstract Background The current study aims to determine cause-specific survival in patients with high-grade osteosarcoma while reporting risk factors for decreased out 10 years. Methods Surveillance, Epidemiology, and End Results (SEER) Program database was used identify all diagnosed from 1991 2010. Patient, tumor, county-level socioeconomic measures were analyzed prognostic survival. Cause-specific 10-year local/regional disease at the time of diagnosis 65.8%, compared 24.0% metastatic disease. Multivariate analysis revealed presentation, age ≥ 60 years, male sex, axial location, size ≥ 10 cm as independent Patients lowest status had a disproportionate frequency large tumors presentation more affluent patients. Conclusions have years when diagnosis, patient tumor measuring ≥ 10 cm. living low counties present frequently tumors. Public health efforts should focus on identifying prior metastasis.