摘要: Osteosarcoma is the most common primary bone malignancy in children. Treatment has evolved to include systemic chemotherapy and local control surgery. Although survival improved initially a drastic fashion with this approach, recent decades have seen little no further gains area. Limb salvage surgery effective advances imaging, continues improve era. This article serves as review of high-grade osteosarcoma: prognostic factors, surgery, late effects survivors, future directions.
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