Cellular aspects of tolerance. VI. The effect of age on responsiveness and tolerance induceability of SJL mice.

作者: Michio Fujiwara , Bernhard Cinader

DOI: 10.1016/0008-8749(74)90073-2

关键词:

摘要: Abstract New born and 3-week-old SJL mice but not 8–12-week-old animals could be rendered tolerant to rabbit γ-globulin. Animals reconstituted with thymus cells from 12-week-old donors bone marrow showed resistance tolerance induction. tolerant. Earlier work has shown that induced in older animals, if they were deprived of competent accessory cells. It was suggested a lesion the cell population is expressed through mediation The possibility relation between induction lymphoid malignancies discussed.

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