Dietary intake and resting energy expenditure in relation to weight loss in unselected cancer patients.

摘要: Weight loss and anorexia are frequent findings in advanced cancer. The progressive wasting could be attributed to changes dietary intake and/or energy expenditure mediated by metabolic alterations. In this study, we analyzed generalized malignant disease of solid tumor type relation resting (REE) reported weight loss. a group 297 unselected cancer patients from university hospital outpatient clinic, macronutrients 4-day food record, REE indirect calorimetry, height, were recorded. Protein was validated against 24 hr urine nitrogen subgroup (n = 53), no indication systematic misreporting found. Mean daily below maintenance requirements, 26 ± 10 kcal/kg. more than 10% present 43% elevated (>110% predicted) 48%. Dietary did not differ between normo- hypermetabolic patients, nor tumour or gender related protein intake. accounted for diminished since absolute amounts different per kilogram body higher weight-losing compared weight-stable patients. macronutrient composition the general population. decreased, but appear changed. hypermetabolism compensated an increase spontaneous Our results indicate that expected up-regulation response is frequently lost This may explanation behind cachexia rather primary decrease appetite. © 2001 Wiley-Liss, Inc.