Poststroke depression and its multifactorial nature: Results from a prospective longitudinal study

摘要: Abstract Objective Poststroke depression (PSD) is commonly observed in stroke patients and has a negative impact on functional outcome quality of life. Therefore, prospective, longitudinal epidemiological study was conducted aiming to determine prevalence risk factors for PSD at 1, 3, 6, 12 18 months poststroke. Methods A total 222 were included the 201 entered data analysis. Demographic data, vascular factors, characteristics, neurocognitive measures psychosocial considered as potential PSD. Clinically significant signs symptoms quantified by means Cornell Scale Depression (CSD) Montgomery Asberg Rating (MADRS). Results present poststroke 24.5%, 27.1%, 28.3%, 19.8% 26.3% respectively. Univariate regression analyses revealed that significantly associated with severity, physical disability, cognitive impairment during time frame study. Reduced social activities presence apraxia consistently whereas aphasia only first 6 months after stroke. Patients relational problems had 3 times greater becoming depressed than without (OR = 3.09; 95% CI = 1.31–7.26). Conclusions Risk seem variable indicating need clinicians consider dynamic multifactorial nature emphasizing importance rigorous long-term monitoring support their caregivers.