Clinical and Histopathologic Evaluation of Six Human Eyes Implanted with the Bag-in-the-Lens

摘要: Purpose To describe the clinical and histopathologic features of eyes implanted with bag-in-the-lens (BIL), which involves use a twin capsulorhexis lens design, performance anterior posterior capsulorhexes. Design Case series clinicopathologic correlation. Participants Six foldable, hydrophilic acrylic BIL, obtained postmortem at different postoperative times, from 4 patients were studied. Methods On patients' death, enucleated, immersed in fixative, submitted for analyses under high-frequency ultrasound unit (Artemis, Ultralink, St. Petersburg, FL; 50 MHz), gross analyses, analyses. Clinical data each case by chart review. Main Outcome Measures included patient demographics, preoperative evaluation, description surgical implantation procedure, outcomes. The evaluation fixation centration, as well capsular bag opacification. Results aged 74.6±12.6 years implantation. time this ranged to 39 months. In all was uneventful (N = 5), BIL decentration insignificant. 1 eye, torn off, although still possible, relative observed postoperatively, but without significance. Although progressively larger amounts Soemmering's ring formation specimens follow-up, central area delimitated rhexis openings remained perfectly clear 6 eyes. Conclusions This is first human times. centration depends on centered capsulorhexes appropriate size. results confirm concept design that any proliferative/regenerative material remains confined intercapsular space remnant outside optic rim. Financial Disclosure(s) Proprietary or commercial disclosure may be found after references.