Mapping on Human and Mouse Chromosomes of the Gene for the β-Galactoside-Binding Protein, an Autocrine-Negative Growth Factor

作者: Antonio Baldini , Thomas Gress , Ketan Patel , Rosella Muresu , Lorenzo Chiariotti

DOI: 10.1006/GENO.1993.1039

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摘要: Abstract The structural gene for β-galactoside-binding protein (Lgals-1), a cell growth regulatory molecule and cystostatic factor, is assigned to the E-region of mouse chromosome 15 region q12-q13.1 human 22. evolutionary conservation these two regions has been previously suggested from comparative mapping several loci. These include murine SIS oncogene (Pdgfb) its homolog, platelet-derived factor-β polypeptide, PDGFB. findings presented here extend genetic homology regions.

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