Localization of immunoglobulin-containing cells in human endometrium in the first trimester of pregnancy and throughout the menstrual cycle

摘要: The distribution of immunoglobulins in normal human endometrium throughout the menstrual cycle and early pregnancy has been studied with an immunoperoxidase technique. In first-trimester decidua, IgG was detected within many cells differing morphology size. Large IgG-containing were often binucleate believed to be decidual cells. Examination serial sections showed no kappa or lambda light-chain restriction, suggesting absorption immunoglobulin content. Medium-sized, irregular, macrophages. An additional substantial population small hyperchromatic prominent around arterioles adjacent endometrial glands. From examination stained phloxine tartrazine, it concluded that these represented granulocytes. Labelling for light chains again suggested contrast, non-pregnant immunoglobulin-containing stromal uncommon, although IgA gland epithelium secretions interstitium particularly secretory phase. These results support notion lacks a classical immune system highlight requirement correlation between studies cell surface markers, receptors.