作者: Lixia Yuan , Ming Li , Fanxing Meng , Yifu Gong , Yunxia Qian
DOI: 10.1016/J.CBPC.2017.08.004
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摘要: Triplicate groups of juvenile yellow catfish Pelteobagrus fulvidraco were exposed to three levels DEHP (0, 0.1 and 0.5mgL-1) for 56days. Fish survival (100%) was not affected by different ambient DEHP. Final body weight, weight gain, specific growth rate feed intake fish 0.5mgL-1 the highest. On contrary, hepatosomatic index lowest. Serum total protein, glutamic-pyruvic transaminase, glutamic-oxaloacetic glucose triglycerides increased with increasing concentrations exposure. Superoxide dismutase glutathione peroxidase activities lowest, but malondialdehyde contents higher than that control fish. Phagocytic indices group After being intraperitoneally injected Aeromonas hydrophila, in had highest expression toll like receptor 5, myeloid differentiation factor 88 This study indicates exerts its toxic effects interfering hepatic metabolism, inducing ROS generation accumulation, leading blood deterioration immunosuppression.