Organic Cation Transporters in Health and Disease.
作者： Hermann Koepsell
关键词:
摘要: The organic cation transporters (OCTs) OCT1, OCT2, OCT3, novel OCT (OCTN) 1, OCTN2, multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …
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N. Pabla, Z. Dong, Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies Kidney International. ,vol. 73, pp. 994- 1007 ,(2008) , 10.1038/SJ.KI.5002786
Mette M.H. Christensen, Rasmus S. Pedersen, Tore B. Stage, Charlotte Brasch-Andersen, Flemming Nielsen, Per Damkier, Henning Beck-Nielsen, Kim Brøsen, A gene-gene interaction between polymorphisms in the OCT2 and MATE1 genes influences the renal clearance of metformin. Pharmacogenetics and Genomics. ,vol. 23, pp. 526- 534 ,(2013) , 10.1097/FPC.0B013E328364A57D
J. William Higgins, David W. Bedwell, Maciej J. Zamek-Gliszczynski, Ablation of both organic cation transporter (OCT)1 and OCT2 alters metformin pharmacokinetics but has no effect on tissue drug exposure and pharmacodynamics. Drug Metabolism and Disposition. ,vol. 40, pp. 1170- 1177 ,(2012) , 10.1124/DMD.112.044875
Y. Cheng, S. H. Wright, M. J. Hooth, I. G. Sipes, Characterization of the disposition and toxicokinetics of N-butylpyridinium chloride in male F-344 rats and female B6C3F1 mice and its transport by organic cation transporter 2. Drug Metabolism and Disposition. ,vol. 37, pp. 909- 916 ,(2009) , 10.1124/DMD.108.022681
Thomas F Solbach, Markus Grube, Martin F Fromm, Oliver Zolk, Organic cation transporter 3: expression in failing and nonfailing human heart and functional characterization. Journal of Cardiovascular Pharmacology. ,vol. 58, pp. 409- 417 ,(2011) , 10.1097/FJC.0B013E3182270783
J. Saura, E. Nadal, B. van den Berg, M. Vila, J.A. Bombi, N. Mahy, Localization of monoamine oxidases in human peripheral tissues. Life Sciences. ,vol. 59, pp. 1341- 1349 ,(1996) , 10.1016/0024-3205(96)00459-6
B Feng, RS Obach, AH Burstein, DJ Clark, SM de Morais, HM Faessel, Effect of human renal cationic transporter inhibition on the pharmacokinetics of varenicline, a new therapy for smoking cessation: an in vitro-in vivo study. Clinical Pharmacology & Therapeutics. ,vol. 83, pp. 567- 576 ,(2008) , 10.1038/SJ.CLPT.6100405
Masahiro Okuda, Hideyuki Saito, Yumiko Urakami, Mikihisa Takano, Ken-ichi Inui, cDNA Cloning and Functional Expression of a Novel Rat Kidney Organic Cation Transporter, OCT2 Biochemical and Biophysical Research Communications. ,vol. 224, pp. 500- 507 ,(1996) , 10.1006/BBRC.1996.1056
Ronald Zwart, Sandra Verhaagh, Marije Buitelaar, Corrie Popp-Snijders, Denise P. Barlow, Impaired activity of the extraneuronal monoamine transporter system known as uptake-2 in Orct3/Slc22a3-deficient mice. Molecular and Cellular Biology. ,vol. 21, pp. 4188- 4196 ,(2001) , 10.1128/MCB.21.13.4188-4196.2001
Andreas Lazar, Susanne Walitza, Alexander Jetter, Manfred Gerlach, Andreas Warnke, Beate Herpertz-Dahlmann, Dirk Gründemann, Gundula Grimberg, Eberhard Schulz, Helmut Remschmidt, Christoph Wewetzer, Edgar Schömig, Novel mutations of the extraneuronal monoamine transporter gene in children and adolescents with obsessive–compulsive disorder The International Journal of Neuropsychopharmacology. ,vol. 11, pp. 35- 48 ,(2008) , 10.1017/S1461145707007742