MicroRNAs in Female Malignancies.

摘要: MicroRNAs (miRNAs) are endogenous 22-nucleotide RNAs that can play a fundamental regulatory role in the gene expression of various organisms. Current research suggests miRNAs assume pivotal roles carcinogenesis. In this article, through bioinformatics mining and computational analysis, we determine single miRNA commonly involved development breast, cervical, endometrial, ovarian, vulvar cancer, whereas underline existence 7 more common all examined malignancies with exception cancer. Furthermore, identify their target genes encoded biological functions. We also analyze processes on which identified act suggest potential mechanism action. addition, exclusive among bioinformatically explore functionality. Collectively, our data be employed vitro assays as stepping stone identification universal machinery is derailed female malignancies, may putative targets for future chemotherapeutic agents or cancer-specific biomarkers.