Determinants of R-loop formation at convergent bidirectionally transcribed trinucleotide repeats
作者： Kaalak Reddy , Mandy Tam , Richard P. Bowater , Miriam Barber , Matthew Tomlinson
DOI: 10.1093/NAR/GKQ935
关键词:
摘要: … Using the t -test to compare R-loop formation revealed a significant difference between the 17 and 53 rCGG R-loop ( P = 0.0413) as well as the 17 and 53 rCCG R-loop ( P = 0.0092). In …
oup.com
uea.ac.uk
paperity.org
oxfordjournals.org参考文章(56)
HD Robertson, JJ Dunn, Ribonucleic acid processing activity of Escherichia coli ribonuclease III. Journal of Biological Chemistry. ,vol. 250, pp. 3050- 3056 ,(1975) , 10.1016/S0021-9258(19)41592-5
Christopher E Pearson, Mandy Tam, Yuh‐Hwa Wang, S Erin Montgomery, Arvin C Dar, John D Cleary, Kerrie Nichol, Slipped‐strand DNAs formed by long (CAG)·(CTG) repeats: slipped‐out repeats and slip‐out junctions Nucleic Acids Research. ,vol. 30, pp. 4534- 4547 ,(2002) , 10.1093/NAR/GKF572
Robert J. Crouch, Ribonuclease III Does Not Degrade Deoxyribonucleic Acid-Ribonucleic Acid Hybrids Journal of Biological Chemistry. ,vol. 249, pp. 1314- 1316 ,(1974) , 10.1016/S0021-9258(19)42977-3
M. Drolet, X. Bi, L.F. Liu, Hypernegative supercoiling of the DNA template during transcription elongation in vitro. Journal of Biological Chemistry. ,vol. 269, pp. 2068- 2074 ,(1994) , 10.1016/S0021-9258(17)42136-3
Yunfu Lin, Sharon YR Dent, John H Wilson, Robert D Wells, Marek Napierala, R loops stimulate genetic instability of CTG·CAG repeats Proceedings of the National Academy of Sciences of the United States of America. ,vol. 107, pp. 692- 697 ,(2010) , 10.1073/PNAS.0909740107
Pablo Huertas, Andrés Aguilera, Cotranscriptionally Formed DNA:RNA Hybrids Mediate Transcription Elongation Impairment and Transcription-Associated Recombination Molecular Cell. ,vol. 12, pp. 711- 721 ,(2003) , 10.1016/J.MOLCEL.2003.08.010
Ahmad M. Khalil, Mohammad Ali Faghihi, Farzaneh Modarresi, Shaun P. Brothers, Claes Wahlestedt, A Novel RNA Transcript with Antiapoptotic Function Is Silenced in Fragile X Syndrome PLoS ONE. ,vol. 3, pp. e1486- ,(2008) , 10.1371/JOURNAL.PONE.0001486
Kefei Yu, Frederic Chedin, Chih-Lin Hsieh, Thomas E. Wilson, Michael R. Lieber, R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells Nature Immunology. ,vol. 4, pp. 442- 451 ,(2003) , 10.1038/NI919
J. Jung, N. Bonini, CREB-Binding Protein Modulates Repeat Instability in a Drosophila Model for PolyQ Disease Science. ,vol. 315, pp. 1857- 1859 ,(2007) , 10.1126/SCIENCE.1139517
Mohammad Ali Faghihi, Claes Wahlestedt, Regulatory roles of natural antisense transcripts Nature Reviews Molecular Cell Biology. ,vol. 10, pp. 637- 643 ,(2009) , 10.1038/NRM2738