Early detection of hepatocellular carcinoma increases the chance of treatment: Hong Kong experience.

摘要: The prognosis for patients with hepatocellular carcinoma (HCC) is poor because of the low chance curative treatment. To increase intervention and to improve survival, early detection subclinical HCC (SCHCC) by alpha-fetoprotein (AFP) and/or ultrasonography (USG) screening implemented in many countries. Three hundred six Chinese diagnosed between January 1995 December 1997 were recruited. They categorized into two groups: 142 (group 1) had SCHCC (AFP USG), 164 2) presented symptomatic HCC. tumor size was significantly smaller group 1 compared that 2 (3.5 cm vs. 8.1 cm; P <.0001). A higher proportion bilobar involvement, multifocal HCC, diffuse-type portal vein infiltration, distant metastasis when 1. Operability feasibility treatment transcatheter intra-arterial chemoembolization (TACE) (26.8% 45.1%, respectively) better than (7.9% 32.3%, <.0001 =.03, respectively). cumulative survival rate (P For those who surgical resection TACE, a =.04 =.0003, Screening AFP USG can identify tumors at an stage, resulting receiving Whether it requires further prospective, randomized study.