Neuraminic acid and its relation to chronic bronchitis III. Carbohydrate constituents of sputum

摘要: Abstract Weak acidic hydrolysis of chronic bronchitis sputum liberated ribose, 2-deoxyribose and fructose together with a mixture four nonosaminic acids including N-acetyl, N,O-diacetyl- N-glycolyl-neuraminic acid. N-acetyl-neuraminic acid was crystallized from the shown by X-ray powder photography, infra-red spectra, decomposition point chromatographic behaviour to be identical an authentic specimen. Stronger galactose, mannose, fucose, hexosamines. One latter characterized as d -glucosamine hydrochloride. A mucoprotein fraction obtained isoelectric precipitation contained (5.4%), glucosamine (12.8%), galactosamine (2.0%) 13.4% total hexoses (galactose, mannose fucose). The amino present in have been identified.