19-nor-3-keto steroids

作者: Lucien Nedelec , Jacques Leclaire , Andre Claussner , Daniel Philibert

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摘要: A compound selected from the group consisting of a formula ##STR1## wherein R 2 and R' are individually hydrogen or methyl, 11 is an organo 1 to 18 carbon atoms optionally containing at least one heteroatom with atom adjacent 11-carbon being carbon, wavy lines 13 17-positions indicate that when 13-methyl α, 17 β α .sub.β, .sub.β --OH acyloxy ##STR2## atoms, Z single bond, alkylene 5 alkenylene alkynylene P pyrimidinyl pyridyl substituted individual members amino, alkylamino dialkylamino 4 alkyl (B aminated 5- 6-membered heterocycle 3 atoms) its non-toxic, pharmaceutically acceptable acid addition salts having anti-inflammatory anti-oxidant activity.

参考文章(1)
Donald E Ayer, Harold A Karnes, John M Mccall, John R Palmer, Doornik Frederick J Van, E Jon Jacobsen, C20 through c26 amino steroids ,(1986)