Metallopeptide combinatorial libraries and applications
作者： Yiqun Shi , Shubh D. Sharma
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摘要: Metallopeptide combinatorial libraries and methods of making metallopeptides are provided for use in biological, pharmaceutical related applications. The made peptides, peptidomimetics peptide-like constructs, include a metal ion-binding region thereof which includes at least one orthogonal sulfur-protecting group, the peptide, peptidomimetic or construct is conformationally fixed on deprotection sulfur complexation with ion. Thereafter library members may be screening to select those desired specificity affinity.
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