Genome editing for treating glioblastoma
作者： Anna M. Krichevsky , Erik J. Uhlmann , Rachid El-Fatimy
DOI:
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摘要: A method of treating a subject who has glioma, e.g., astrocytoma, oligodendroglioma, or glioblastoma multiforme tumor, the comprising administering to therapeutically effective amount Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) microRNA-10b (miR-10b) editing complex CRISPR Associated Protein 9 (Cas9) and at least one guide RNA targeting sequence encoding miR-10b.
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