[Assessment of airway inflammation in chronic obstructive pulmonary disease: biomarkers in exhaled breath condensate].
作者： Balázs Antus
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摘要: A leguti gyulladas kozponti szerepet jatszik a kronikus obstruktiv tudőbetegseg patofiziologiajaban. cigarettafust-expozicio gyulladasos sejtek infiltraciojat okozza legutakban, amely kulonboző citokinek, kemokinek, proteazok es proinflammatorikus mediatorok felszabadulasahoz vezet, vegul az oxidativ stressz proteaz/antiproteaz egyensuly megbomlasa tudő szoveteinek progressziv karosodasat eredmenyezi. biomarkerek felhasznalhatok monitorozasara, betegseg fenotipusainak elkulonitesere terapias beavatkozasok hatekonysaganak megitelesere. kilegzett levegő kondenzatumanak gyűjtese egyszerű teljesen noninvaziv modszer legutakban zajlo folyamatok vizsgalatara. kondenzatumaban szamos biomarker talalhato, tobbek kozott hidrogen-peroxid, arachidonsav-metabolitok, nitrogen-oxidok pH. sok esetben igen kis koncentracioban vannak jelen, analitikai problemat vet fel. klinikai...
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