Antibody engineering for the development of therapeutic antibodies.

作者: Hyo Jeong Hong , Young Woo Park , Sang Jick Kim

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摘要: Therapeutic antibodies represent one of the fastest growing areas pharmaceutical industry. There are currently 19 monoclonal in market that have been approved by FDA and over 150 clinical developments. Driven innovation technological developments, therapeutic second largest biopharmaceutical product category after vaccines. Antibodies engineered a variety methods to suit particular use. This review describes structural functional characteristics antibody engineering for generation optimization antibodies.

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