LOCALIZATION OF THE ANDROGEN RECEPTOR IN THE DEVELOPING RAT GUBERNACULUM
作者： D. A. HUSMANN , M. J. MCPHAUL
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摘要: The distribution of androgen receptor expression within the developing rat gubernaculum was examined at different times during fetal and neonatal development using polyclonal antibodies directed amino-terminus (amino acids 1–21) carboxy-terminus 898–917) receptor. These studies reveal a high level in undifferentiated cells that comprise mesenchymal core early development. However, morphological alterations into muscular structure, detected these declines, with minimal immunoreactivity present 2 weeks postpartum. Whether loss staining mesenchyme is related to decreases expression, death cells, or differentiation myoblasts remains be determined. (Endocrinology 128: 383–387, 1991)
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DOUGLAS A. HUSMANN, CAROL M. WILSON, MICHAEL J. McPHAUL, WAYNE D. TILLEY, JEAN D. WILSON, Antipeptide antibodies to two distinct regions of the androgen receptor localize the receptor protein to the nuclei of target cells in the rat and human prostate. Endocrinology. ,vol. 126, pp. 2359- 2368 ,(1990) , 10.1210/ENDO-126-5-2359
A.C. Oprins, J.M.Fentener van Vlissingen, M.A. Blankenstein, Testicular descent: androgen receptors in cultured porcine gubernaculum cells. Journal of Steroid Biochemistry. ,vol. 31, pp. 387- 391 ,(1988) , 10.1016/0022-4731(88)90306-8
Howard L. Frey, Susy Peng, Jacob Rajfer, Synergy of abdominal pressure and androgens in testicular descent. Biology of Reproduction. ,vol. 29, pp. 1233- 1239 ,(1983) , 10.1095/BIOLREPROD29.5.1233
FREDRICK W. GEORGE, Developmental Pattern of 5α-Reductase Activity in the Rat Gubernaculum* Endocrinology. ,vol. 124, pp. 727- 732 ,(1989) , 10.1210/ENDO-124-2-727
R. J. SANTEN, C. ALVIN PAULSEN, Hypogonadotropic Eunuchoidism. II. Gonadal Responsiveness to Exogenous Gonadotropins The Journal of Clinical Endocrinology and Metabolism. ,vol. 36, pp. 55- 63 ,(1973) , 10.1210/JCEM-36-1-55
S M Hsu, L Raine, H Fanger, Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. Journal of Histochemistry and Cytochemistry. ,vol. 29, pp. 577- 580 ,(1981) , 10.1177/29.4.6166661
Fredrick W. George, Kirk G. Peterson, Partial characterization of the androgen receptor of the newborn rat gubernaculum. Biology of Reproduction. ,vol. 39, pp. 536- 539 ,(1988) , 10.1095/BIOLREPROD39.3.536
C. Wayne Bardin, Griff T. Ross, Arleen B. Rifkind, Charles M. Cargille, Mortimer B. Lipsett, Studies of the pituitary-Leydig cell axis in young men with hypogonadotropic hypogonadism and hyposmia: comparison with normal men, prepuberal boys, and hypopituitary patients Journal of Clinical Investigation. ,vol. 48, pp. 2046- 2056 ,(1969) , 10.1172/JCI106170
Jack S. Elder, John T. Isaacs, Patrick C. Walsh, Androgenic Sensitivity of the Gubernaculum Testis: Evidence for Hormonal/Mechanical Interactions in Testicular Descent The Journal of Urology. ,vol. 127, pp. 170- 176 ,(1982) , 10.1016/S0022-5347(17)53655-1
Howard L. Frey, Jacob Rajfer, Role of the gubernaculum and intraabdominal pressure in the process of testicular descent. The Journal of Urology. ,vol. 131, pp. 574- 579 ,(1984) , 10.1016/S0022-5347(17)50507-8