Mitochondrial Energy Metabolism in Chronic Alcoholism

摘要: Publisher Summary This chapter discusses the mitochondrial energy metabolism in chronic alcoholism. Long-term intake of large amounts ethanol has deleterious effects on multiple organs body. It is associated with diseases liver, heart, skeletal muscle, pancreas, brain, and other tissues, compromised host defence mechanisms tissue repair capacities. Almost all parameters that contribute to control conservation are affected when tissues exposed acutely and, depending tissue, changes these components may occur response intake. For instance, oxidation liver causes a marked change redox state both cytosolic NAD. affects flux electrons from substrates, for example, fatty acids into tricarboxylic acid cycle (TCA) metabolite transfer processes shuttling reducing equivalents NADH respiratory chain.