Polymer brush controlled bioinspired calcium phosphate mineralization and bone cell growth.
作者： Ruben Löbbicke , Munish Chanana , Helmut Schlaad , Christine Pilz-Allen , Christina Günter
DOI: 10.1021/BM200991B
关键词:
摘要: Polymer brushes on thiol-modified gold surfaces were synthesized by using terminal thiol groups for the surface-initiated free radical polymerization of methacrylic acid and dimethylaminoethyl methacrylate, respectively. Atomic force microscopy shows that resulting poly(methacrylic acid) (PMAA) poly(dimethylaminoethyl methacrylate) (PDMAEMA) are homogeneous. Contact angle measurements show pH-responsive can reversibly be protonated deprotonated. Mineralization with calcium phosphate at different pH yields homogeneously mineralized surfaces, preosteoblastic cells proliferate both nonmineralized surfaces. The number living hybrid is ca. 3 times 10 higher than corresponding brushes.
acs.org
core.ac.uk
mpg.de
sci-hub.se 参考文章(47)
우희권, 박선희, 홍란영, 강행구, 함희숙, None, Photopolymerization of Methacrylic Acid with Secondary Silanes Bulletin of The Korean Chemical Society. ,vol. 17, pp. 532- 535 ,(1996)
L. M. Abrantes, V. C. Ferreira, F. Silva, Electrochemical and STM Study of α,ω-alkanedithiols Self-assembled Monolayers Chemical and Biochemical Engineering Quarterly. ,vol. 23, pp. 99- 106 ,(2009)
Jadwiga Matuszewska-Czerwik, Stefan Połowiński, Photopolymerization of methacrylic acid on photoinitiator templates Die Makromolekulare Chemie, Rapid Communications. ,vol. 10, pp. 513- 516 ,(1989) , 10.1002/MARC.1989.030101002
G.K. Toworfe, R.J. Composto, I.M. Shapiro, P. Ducheyne, NUCLEATION AND GROWTH OF CALCIUM PHOSPHATE ON AMINE, CARBOXYL- AND HYDROXYL-SILANE SELF-ASSEMBLED MONOLAYERS Biomaterials. ,vol. 27, pp. 631- 642 ,(2006) , 10.1016/J.BIOMATERIALS.2005.06.017
Mark H. Schoenfisch, Jeanne E. Pemberton, Air Stability of Alkanethiol Self-Assembled Monolayers on Silver and Gold Surfaces Journal of the American Chemical Society. ,vol. 120, pp. 4502- 4513 ,(1998) , 10.1021/JA974301T
T. R. Anantharaman, C. Suryanarayana, Review: A decade of quenching from the melt Journal of Materials Science. ,vol. 6, pp. 1111- 1135 ,(1971) , 10.1007/BF00980610
Vincent Ball, Marc Michel, Fouzia Boulmedais, Joseph Hemmerle, Youssef Haikel, Pierre Schaaf, Jean Claude Voegel, Nucleation Kinetics of Calcium Phosphates on Polyelectrolyte Multilayers Displaying Internal Secondary Structure Crystal Growth & Design. ,vol. 6, pp. 327- 334 ,(2006) , 10.1021/CG050044P
Chang Du, Janet Moradian-Oldak, Tooth regeneration: challenges and opportunities for biomedical material research. Biomedical Materials. ,vol. 1, ,(2006) , 10.1088/1748-6041/1/1/R02
Maja Dutour Sikirić, Csilla Gergely, Rene Elkaim, Ellen Wachtel, Frederic J. G. Cuisinier, Helga Füredi-Milhofer, Biomimetic organic-inorganic nanocomposite coatings for titanium implants. Journal of Biomedical Materials Research Part A. ,vol. 89, pp. 759- 771 ,(2009) , 10.1002/JBM.A.32021
M.A. Walters, Y.C. Leung, N.C. Blumenthal, K.A. Konsker, R.Z. LeGeros, A Raman and infrared spectroscopic investigation of biological hydroxyapatite. Journal of Inorganic Biochemistry. ,vol. 39, pp. 193- 200 ,(1990) , 10.1016/0162-0134(90)84002-7