Nucleation Kinetics of Calcium Phosphates on Polyelectrolyte Multilayers Displaying Internal Secondary Structure

摘要: The understanding of the role biological macromolecules in nucleation calcium carbonates and phosphates is primary importance for development biomimetic surfaces able to mimic proteins used by living organisms produce such composite materials. In this study we show how polyelectrolyte multilayers made from poly-l-lysine (PLL) as polycation a mixture two polyanions, poly-l-glutamic acid (PGA) poly-l-aspartic (Pasp), at different ratios are affect duration lag time preceding crystal growth constant supersaturation. These appear interesting candidates surfaces, since they display content β-sheets that can be controlled changing PGA proportion polyanion mixture. times fast measured situ with three complementary techniques, namely quartz microbalance dissipation (QCM-D), optical waveguide lightmode ...