Prognostic value of ST-segment resolution-when and what to measure.

作者: Per Johanson , Tomas Jernberg , Gunnar Gunnarsson , Bertil Lindahl , Lars Wallentin

DOI: 10.1016/S0195-668X(02)00739-X

关键词:

摘要: Aims Analyses of ST-segment resolution during acute myocardial infarction has, recent years, challenged coronary angiography as gold-standard for predictingmyocardial reflow and future risk. We have previously reported that continuous ST-monitoring can be done accurately in the clinical setting. now set out to compare prognostic value suggested cut-offs ST-segmentresolution, determine times measure these. Methods results analysed 752 patients with ST-elevation infarction, from second Assessment Safety Efficacy a New Thrombolytic (ASSENT 2) ASSENT-PLUS studies, either vectorcardiography or 12-lead ST-monitoring. All analyses were made blindly by two independent observers. Times 20, 30, 50 70% examined relation 30-day mortality. The optimal cut-off was found 50%, measured at 60min. could hereby identify large low-risk group, 40% population, only 1.4% mortality. Furthermore, 88% deaths correctly predicted within 1h observation treatment. Conclusion Continuous yields important information after 60min should used very early-risk stratification these patients.

参考文章(31)
Rolf Schröder, Karl Wegscheider, Klaus Schröder, Rüdiger Dissmann, Wolfgang Meyer-Sabellek, Extent of early ST segment elevation resolution: A strong predictor of outcome in patients with acute myocardial infarction and a sensitive measure to compare thrombolytic regimens Journal of the American College of Cardiology. ,vol. 26, pp. 1657- 1664 ,(1995) , 10.1016/0735-1097(95)00372-X
Akbar Shah, Galen S Wagner, Christopher B Granger, Christopher M O’Connor, Cynthia L Green, Kathleen M Trollinger, Robert M Califf, Mitchell W Krucoff, Prognostic implications of TIMI flow grade in the infarct related artery compared with continuous 12-lead ST-segment resolution analysis. Reexamining the "gold standard" for myocardial reperfusion assessment. Journal of the American College of Cardiology. ,vol. 35, pp. 666- 672 ,(2000) , 10.1016/S0735-1097(99)00601-4
Anatoly Langer, Mitchell W Krucoff, Peter Klootwijk, Maarten L Simoons, Christopher B Granger, Aiala Barr, Robert M Califf, Paul W Armstrong, GUSTO-I ECG Monitoring Substudy Group 2, Prognostic significance of ST segment shift early after resolution of ST elevation in patients with myocardial infarction treated with thrombolytic therapy : The GUSTO-I ST segment monitoring substudy Journal of the American College of Cardiology. ,vol. 31, pp. 783- 789 ,(1998) , 10.1016/S0735-1097(97)00544-5
Francesco Mauri, Aldo Pietro Maggioni, Maria Grazia Franzosi, Claudio De Vita, Eugenio Santqro, Luigi Santoro, Pantaleo Giannuzzi, Gianni Tognoni, A simple electrocardiographic predictor of the outcome of patients with acute myocardial infarction treated with a thrombolytic agent Journal of the American College of Cardiology. ,vol. 24, pp. 600- 607 ,(1994) , 10.1016/0735-1097(94)90003-5
L. BOSSAERT, V. CONRAADS, H. PlNTENS, ST-segment analysis: a useful marker for reperfusion after thrombolysis with APS AC? European Heart Journal. ,vol. 12, pp. 357- 362 ,(1991) , 10.1093/OXFORDJOURNALS.EURHEARTJ.A059902
Per Johanson, Karl Swedberg, Mikael Dellborg, ST variability during the first 4 hours of acute myocardial infarction predicts 1-year mortality. Annals of Noninvasive Electrocardiology. ,vol. 6, pp. 198- 202 ,(2001) , 10.1111/J.1542-474X.2001.TB00108.X
P. Klootwijk, A. Langer, S. Meij, C. Green, R. F. Veldkamp, A. M. Ross, P. W. Armstrong, M. L. Simoons, , Non-invasive prediction of reperfusion and coronary artery patency by continuous ST segment monitoring in the GUSTO-I trial. European Heart Journal. ,vol. 17, pp. 689- 698 ,(1996) , 10.1093/OXFORDJOURNALS.EURHEARTJ.A014935
Ki-ik Kwon, S.Benedict Freedman, Ian Wilcox, Kevin Allman, Ann Madden, Grant S. Carter, Phillip J. Harris, The unstable ST segment early after thrombolysis for acute infarction and its usefulness as a marker of recurrent coronary occlusion American Journal of Cardiology. ,vol. 67, pp. 109- 115 ,(1991) , 10.1016/0002-9149(91)90430-S
Mitchell W. Krucoff, Curtis E. Green, Lowell F. Satler, Frederick C. Miller, Randolph S. Pallas, Kenneth M. Kent, Albert A. Del Negro, David L. Pearle, Ross D. Fletcher, Charles E. Rackley, Noninvasive detection of coronary artery patency using continuous ST-segment monitoring American Journal of Cardiology. ,vol. 57, pp. 916- 922 ,(1986) , 10.1016/0002-9149(86)90730-7