Mean platelet volume is a predictor of ST resolution following thrombolysis in acute ST elevation myocardial infarction

作者: Samad Ghaffari , Leili Pourafkari , Hassan Javadzadegan , Nayyer Masoumi , Mohammad Asghari Jafarabadi

DOI: 10.1016/J.THROMRES.2015.05.003

关键词: In patientMyocardial infarctionThrombolysisSt elevation myocardial infarctionMedicineMaceMean platelet volumeCardiologyEmergency departmentInternal medicine

摘要: Abstract Background Larger mean platelets volumes (MPV) are thrombogenic and frequently seen after ST-segment elevation myocardial infarction (STEMI). This study aimed to examine the association of MPV resolution thrombolysis in STEMI patients as its impact on clinical outcome. Methods Patients presenting emergency department with diagnosis first were referred screened. ≥ 50% (STR) 90 minutes assigned “Responder” those Results STR ≥ 50% was 60.2% thrombolysis. Responders had significantly lower (P = 0.001) critical values 8.0 femtoliter (fL) 8.2 fL predicting STR MACE. ≥ 8.2 fL probability higher rates AHF (P  Conclusion Higher MPV’s at admission associated occurrence major adverse cardiac events receiving thrombolytic therapy for time STEMI.

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