Efficacy of epidural steroid injections for low-back pain and sciatica: a systematic review of randomized clinical trials

作者: Bart W. Koes , Rob J.P.M. Scholten , Jan M.A. Mens , Lex M. Bouter

DOI: 10.1016/0304-3959(95)00124-7

关键词:

摘要: The purpose of the study was to assess efficacy epidural steroid injections for low-back pain. Data obtained using computer-aided search published randomized clinical trials and assessment methods studies. Twelve evaluating were identified. extracted based on scores quality methods, 4 categories (study population, interventions, effect measurement, data presentation analysis) conclusion author(s) with regard injections. Method ranged from 17 72 points (maximum 100 points). Eight showed method 50 or more. Of best studies (> 60 points), 2 reported positive outcomes negative results. Overall, 6 indicated that injection more effective than reference treatment it be no better worse treatment. There appeared relationship between methodological outcomes. In conclusion, there are flaws in design most inconsistent results has not been established. benefits injections, if any, seem short duration only. Future research efforts warranted, but attention should paid trials.

参考文章(34)
J M Cuckler, P A Bernini, S W Wiesel, R E Booth, R H Rothman, G T Pickens, The use of epidural steroids in the treatment of lumbar radicular pain. A prospective, randomized, double-blind study. Journal of Bone and Joint Surgery, American Volume. ,vol. 67, pp. 63- 66 ,(1985) , 10.2106/00004623-198567010-00009
Richard A. Deyo, Conservative Therapy for Low Back Pain JAMA. ,vol. 250, pp. 1057- 1062 ,(1983) , 10.1001/JAMA.1983.03340080035024
G. ter Riet, J. Kleunen, P. Knipschild, ACUPUNCTURE AND CHRONIC PAIN : A CRITERIA-BASED META-ANALYSIS Journal of Clinical Epidemiology. ,vol. 43, pp. 1191- 1199 ,(1990) , 10.1016/0895-4356(90)90020-P
Angelo G. Rocco, Evan Frank, Alan F. Kaul, Stephen J. Lipson, Jeffrey P. Gallo, Epidural steroids, epidural morphine and epidural steroids combined with morphine in the treatment of post-laminectomy syndrome. Pain. ,vol. 36, pp. 297- 303 ,(1989) , 10.1016/0304-3959(89)90088-2
Bart W Koes, Maurits W van Tulder, Danielle AWM Van Der Windt, Lex M Bouter, None, The Efficacy of Back Schools - A Review of Randomized Clinical-Trials Journal of Clinical Epidemiology. ,vol. 47, pp. 851- 862 ,(1994) , 10.1016/0895-4356(94)90188-0
D. A. Nelson, Dangers From Intraspinal Steroid Injections JAMA Neurology. ,vol. 47, pp. 255- 255 ,(1990) , 10.1001/ARCHNEUR.1990.00530030019009
S. J. Bowman, L. Wedderburn, A. Whaley, R. Grahame, S. Newman, Outcome assessment after epidural corticosteroid injection for low back pain and sciatica. Spine. ,vol. 18, pp. 1345- 1350 ,(1993) , 10.1097/00007632-199308000-00014