Internet-based guided self-help for glioma patients with depressive symptoms: A randomized controlled trial

摘要: Background: Among glioma patients, depression is estimated to be more prevalent than in both the general population and cancer patient population. This can have negative consequences for patients their primary informal caregivers (e.g., a spouse, family member or close friend). At present, there no evidence from randomized controlled trials effectiveness of psychological treatment patients. Furthermore, possibility delivering mental health care through internet has not yet been explored this Therefore, trial warranted evaluate effects an internet-based, guided self-help intervention depressive symptoms Methods/design: The based on problem-solving therapy. An existing 5-week course adapted use by adult with mild moderate (Center Epidemiology Studies Depression Scale score ≥12). Sample size calculations yield 126 included, who are randomly assigned either group waiting list control group. In addition, we aim include 63 haematological non-central nervous system malignancy Assessments take place at baseline, after 6 12 weeks, months. Primary outcome measure change symptoms. Secondary measures health-related quality life, fatigue, costs satisfaction. all asked assign caregiver, does participate but complete similar assessments. Their mood, life fatigue evaluated as well. Discussion: first study therapy delivered If proven effective, will contribute clinical practice.