Compositions and methods for adoptive cell therapy for cancer

作者: David A. Scheinberg , Derek S. Tan , Thomas J. Gardner , Jonghan Lee , Ivo Lorenz

DOI:

关键词:

摘要: Provided herein are compositions and methods for adoptive cell therapy comprising engineered immune cells that express a tumor antigen-targeted chimeric antigen receptor prodrug converting enzyme.

参考文章(8)
Penka Slavtcheva Slavova-Petrova, Xinli Pang, Robert Adam Uger, Treatment of cd47+ disease cells with sirp alpha-fc fusions ,(2013)
Xiufeng Wu, Lisa J. Croner, Scott Glaser, Brian Robert Miller, William B. Snyder, Norman Wang, Alexey Alexandrovich Lugovskoy, Stephen Demarest, Stabilized polypeptide compositions ,(2007)
Kevin Pinz, Masayuki Wada, Kevin Chen, Xun Jiang, Yupo Ma, CHIMERIC ANTIGEN RECEPTORS (CARs), COMPOSITIONS AND METHODS OF USE THEREOF ,(2016)
David A. Scheinberg, K. Christopher Garcia, Melissa Mathias, Jonathan Thomas Sockolosky, Cd47 blockade enhances therapeutic activity of antibodies to low density cancer epitopes ,(2017)
Stephen M. G. Gottschalk, Felicia Cao, Cancer gene therapy targeting cd47 ,(2017)
Renier J. Brentjens, Hollie J. Jackson, Compositions and methods for immunotherapy ,(2014)