Agglomerated novel spray-dried lactose-leucine tailored as a carrier to enhance the aerosolization performance of salbutamol sulfate from DPI formulations.

作者: Carlos Molina , Waseem Kaialy , Qiao Chen , Daniel Commandeur , Ali Nokhodchi

DOI: 10.1007/S13346-017-0462-8

关键词:

摘要: Spray-drying allows to modify the physicochemical/mechanical properties of particles along with their morphology. In the present study, L -leucine with varying concentrations (0.1, 0.5, 1…

参考文章(42)
PETER R. BYRON, JOHN S. PATTON, DRUG DELIVERY VIA THE RESPIRATORY TRACT Journal of Aerosol Medicine-deposition Clearance and Effects in The Lung. ,vol. 7, pp. 49- 75 ,(1993) , 10.1089/JAM.1994.7.49
R.P. Aquino, L. Prota, G. Auriemma, A. Santoro, T. Mencherini, G. Colombo, P. Russo, Dry powder inhalers of gentamicin and leucine: formulation parameters, aerosol performance and in vitro toxicity on CuFi1 cells. International Journal of Pharmaceutics. ,vol. 426, pp. 100- 107 ,(2012) , 10.1016/J.IJPHARM.2012.01.026
Philippe Begat, Robert Price, Haggis Harris, David A.V. Morton, John N. Staniforth, The Influence of Force Control Agents on the Cohesive-Adhesive Balance in Dry Powder Inhaler Formulations Kona Powder and Particle Journal. ,vol. 23, pp. 109- 121 ,(2005) , 10.14356/KONA.2005014
Birju Shah, Vasu Kumar Kakumanu, Arvind K. Bansal, Analytical techniques for quantification of amorphous/crystalline phases in pharmaceutical solids. Journal of Pharmaceutical Sciences. ,vol. 95, pp. 1641- 1665 ,(2006) , 10.1002/JPS.20644
Basma M. Ibrahim, Seoung Wook Jun, Mee Yong Lee, Soo Hyung Kang, Yoon Yeo, Development of inhalable dry powder formulation of basic fibroblast growth factor International Journal of Pharmaceutics. ,vol. 385, pp. 66- 72 ,(2010) , 10.1016/J.IJPHARM.2009.10.029
Jagdeep Shur, Robert Price, Advanced microscopy techniques to assess solid-state properties of inhalation medicines. Advanced Drug Delivery Reviews. ,vol. 64, pp. 369- 382 ,(2012) , 10.1016/J.ADDR.2011.11.005
S.P. NEWMAN, W.W. BUSSE, Evolution of dry powder inhaler design, formulation, and performance Respiratory Medicine. ,vol. 96, pp. 293- 304 ,(2002) , 10.1053/RMED.2001.1276
Hsu-Chi Yeh, G. M. Schum, Models of human lung airways and their application to inhaled particle deposition Bulletin of Mathematical Biology. ,vol. 42, pp. 461- 480 ,(1980) , 10.1007/BF02460796
E. Kaminska, K. Adrjanowicz, K. Kaminski, P. Wlodarczyk, L. Hawelek, K. Kolodziejczyk, M. Tarnacka, D. Zakowiecki, I. Kaczmarczyk-Sedlak, J. Pilch, M. Paluch, A New Way of Stabilization of Furosemide upon Cryogenic Grinding by Using Acylated Saccharides Matrices. The Role of Hydrogen Bonds in Decomposition Mechanism Molecular Pharmaceutics. ,vol. 10, pp. 1824- 1835 ,(2013) , 10.1021/MP300606P
Lucia Prota, Antonietta Santoro, Maurizio Bifulco, Rita P. Aquino, Teresa Mencherini, Paola Russo, Leucine enhances aerosol performance of Naringin dry powder and its activity on cystic fibrosis airway epithelial cells International Journal of Pharmaceutics. ,vol. 412, pp. 8- 19 ,(2011) , 10.1016/J.IJPHARM.2011.03.055