Association Between Recent Overnight Travel and Risk of Malaria: A Prospective Cohort Study at 3 Sites in Uganda.

摘要: Background: Human movement can undermine malaria control efforts. However, understanding of the association between travel and infection in Africa is limited. We evaluated recent overnight incidence Uganda. Methods: All children aged 0.5-10 years 1 adult living 266 randomly selected households within 3 different regions Uganda were followed up prospectively. Information on was collected 2015-2016. Malaria, defined as fever with parasites detected by microscopy, measured using passive surveillance. Results: At least trip reported 64 275 (23.3%) participants Walukuba, 37 317 (11.7%) Nagongera, 19 314 (6.1%) Kihihi. Among individuals who traveled, higher first 60 days after traveling, compared periods without at all sites (overall, 1.15 vs 0.33 episodes per person-year; rate ratio, 3.53; 95% confidence interval, 1.85-6.73; P < .001). Risk factors for included young age (19.5% 4.9% adults; odds 5.29; 1.34-21.0; = .02) not an insecticide-treated net during (18.0% no use 4.1% any use; 5.10; 1.07-24.5; .04). Conclusions: Recent associated a malaria. Individuals may represent high-risk group that could be targeted interventions, particularly nets.