Effects of treatment with St. John's Wort on blood glucose levels and pain perceptions of streptozotocin-diabetic rats.
作者： Özgür Devrim Can , Yusuf Öztürk , Nilgün Öztürk , Gianni Sagratini , Massimo Ricciutelli
DOI: 10.1016/J.FITOTE.2011.01.008
关键词:
摘要: This present study was undertaken to examine treating effects of St. John's Wort (SJW) extract on nociceptive perception STZ-diabetic animals based its potential antidiabetic and antinociceptive activities. One week administrations SJW (125 250 mg/kg) induced significant decrease in high blood glucose levels three weeks rats improved their dysregulated metabolic parameters. In addition, treatment caused restoration the mechanical hyperalgesia diabetic animals. These findings provide a rationale for traditional use against diabetes display this plant as new drug candidate/source pain.
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