Angiogenesis in human gliomas: prognostic and therapeutic implications.

摘要: Angiogenesis is fundamental to the growth of all solid tumors, and efforts at elucidating critical elements this process have yielded a wealth information about biology, clinical behavior potential treatment these neoplasms. This particularly relevant for brain which are among most highly vascular human neoplasms, undoubtedly much what known systemic cancers also applies tumors. However, factors must be evaluated differently with regard tumors central nervous system within context unique character cerebrovascular physiology glioma biology. The nature significance angiogenesis yet fully explored, but already important insights into its implications been developed. Further clarification association between holds exciting promise novel anti-angiogenic strategies therapy.