Physical activity and low-fat diet: is it enough to maintain weight stability in the reduced-obese individual following weight loss by drug therapy and energy restriction?

摘要: DOUCET, ERIC, PASCAL IMBEAULT, NATALIE ALMERAS, AND ANGELO TREMBLAY. Physical activity and low-fat diet: Is it enough to maintain weight stability in the reduced-obese individual following loss by drug therapy energy restriction? Obes Res. Objective: The anthropometric physiological effects of a physical (PA) mildly energy-restricted diet (LFD) follow-up program after long-term dietary restriction were studied 12 men 8 women. Research Methods Procedures: (−700 kcal/day) was accompanied fenfluramine (60 mg/day) or placebo treatment for 15 weeks, whereas mean duration PA-LFD 18 weeks. Results: reduced body (−11. 9 −7. 6 kg, p<. 001), fat mass (FM) (−10. −5. p<0. 01), resting metabolic rate (RMR) (−304 kcal/day, 01 −148 NS) women, respectively. A decrease fat-free (FFM) also observed women (−1. 05). preserved at caused an additional significant FM (−3. 4 This part intervention increase daily RMR (134 point where this value no longer differed from pre-energy value. In contrast, further (−200 Significantly initial values (p<0. 01). Resting seated heart leading differ significantly both pre- post-energy (−8. 5 bpm, 01). Discussion: conclusion, these results suggest that has potential permit may even accentuate state. Moreover, expenditure is increased under such conditions men. These stimulating seem be specific metabolism since either remained stable response follow-up.